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Moderate-StrongEnergy and fatigue

What to eat when perimenopause is draining your energy

Iron, magnesium, B12, vitamin D, and protein. The nutrients that address perimenopause fatigue directly.

10 min · Nutrition

The fatigue is real

Perimenopause fatigue is not tiredness from a bad night. It is a persistent, bone-deep depletion. Multiple mechanisms: oestrogen regulates mitochondrial function, sleep disruption accumulates, and muscle loss increases the metabolic cost of every activity.

Priority nutrients

Iron (4/5 Strong) — Heavy periods accelerate iron depletion. Get iron tested before supplementing. Ferritin below 50 is associated with fatigue even when haemoglobin is normal.

Magnesium (4/5 Strong) — Involved in ATP synthesis. 200-400mg glycinate daily.

B12 and B6 (3/5 Moderate) — B12 deficiency causes fatigue clinically indistinguishable from perimenopause fatigue. Worth testing.

Vitamin D (3/5 Moderate) — Low vitamin D is associated with fatigue and muscle weakness. 1,000-2,000 IU daily.

Protein (5/5 Very Strong) — 1.2-1.6g per kg body weight. Supports muscle maintenance.

Foods that support this pattern

Include more: Red meat 2-3 times per week, eggs, legumes, dark leafy greens, whole grains, nuts and seeds.

Include less: High-sugar foods, processed carbohydrates, alcohol.

Should you test before you supplement?

For iron and vitamin D: yes. Testing prevents both under-supplementing and over-supplementing.

For magnesium: blood tests are unreliable. Treat based on symptoms and dietary intake.

Evidence summary

OutcomeGradeNotes
Iron for fatigueStrongTest before supplementing
Magnesium for energyStrongEFSA-approved claim
B12 for fatigueModerateTest if over 45 or vegetarian
Protein for muscleVery StrongHighest-impact intervention

Medical disclaimer

Persistent fatigue should be investigated by a GP to rule out thyroid conditions, anaemia, and sleep disorders. Summ is not a medical service.

References

EFSA (2010-2012). Nutrient health claims.

Barbagallo et al. (2023). Magnesium and women's health. Nutrients.

Traber et al. (2023). Iron deficiency and fatigue. Current Opinion.

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